organoid engineering PostDoc positions and fellowships

This postdoctoral fellowship in the Holford Laboratory at Harvard University focuses on developing novel molluscan cell lines and organoid systems to study cephalopod and conoidean venom glands and venom gene families. The fellow will establish long-term molluscan cell culture, optimize culture media, apply molecular and genomic techniques, utilize gene-editing approaches, and conduct imaging, transcriptomic, proteomic, and functional analyses. Collaboration across biology, engineering, and translational research is expected, along with mentoring graduate students and preparing manuscripts and grant applications.

The Holford Laboratory at Harvard University seeks a Postdoctoral Fellow to pioneer the development of novel molluscan cell lines and organoid systems for marine invertebrate biology, environmental adaptation, and biotechnology applications. The fellow will establish long-term molluscan cell culture, derive organoids from tissues and stem cells, and formulate specialized culture media. Using molecular, cellular, genomic, and gene-editing techniques, the fellow will characterize cell identity, differentiation, and function, while conducting imaging, transcriptomic, proteomic, and functional analyses. The role also involves collaboration across biology, engineering, and translational teams, mentoring graduate students and junior staff, and preparing manuscripts, presentations, and grant applications focused on cephalopod and conoidean venom glands and venom gene families.

This postdoctoral position focuses on developing novel region-specific cortical organoid models from induced pluripotent stem (iPS) cells to study human cortex development and neurodevelopmental disorders. The successful candidate will differentiate iPS cells into cortical organoids that replicate cellular diversity and organization using microfluidic devices designed within the team, and will characterize the resulting cells via immunofluorescence and transcriptomic analyses. The role is situated within the Physique des Cellules et Cancer (UMR168) laboratory at Institut Curie in Paris, offering a highly interdisciplinary environment that combines physics, biology, biochemistry, and microbiology.

This PhD position at ETH Zurich’s Singapore-ETH Centre focuses on developing advanced patient-derived bone organoids to model osteoporosis and fracture risk. The researcher will 3D print mesenchymal stromal cells, guide osteogenic differentiation under mechanical stimulation, and co-culture with peripheral blood mononuclear cells to study immune-bone interactions, donor-specific phenotypes, and mineralisation dynamics. Work involves molecular, biochemical, histological, imaging, and biomechanical techniques, complemented by computational analysis using Python and image processing. The project aims to create predictive models for personalised musculoskeletal care and fracture prevention strategies.

The ON‑Chip project seeks a postdoctoral researcher to design and fabricate micro‑ and millifluidic chips that recreate a human optic nerve‑on‑a‑chip platform. The work involves soft lithography, hot embossing, and clean‑room microfabrication to create fluidic channels linking retinal organoids to brain assembloids, incorporating microglial cells and genetically encoded biosensors for real‑time monitoring of retinal ganglion cell homeostasis under glaucomatous conditions such as neuroinflammation and elevated intra‑ocular pressure. The position is based at the Neuro‑SU department of CNRS in Paris, collaborating with Institut de la Vision and Institut du Cerveau, and is funded by the French PEPR MED‑OOC exploratory research program.

The Ohio State University seeks a highly motivated Postdoctoral Scholar to join the Thege Laboratory in the Division of Surgical Oncology. The position focuses on developing rational drug combinations for KRAS‑mutant pancreatic and lung cancers, using patient‑derived organoids, genetically engineered mouse models, CRISPR activation screens, and multi‑omic profiling (scRNA‑seq, spatial transcriptomics, bulk RNA‑seq) to uncover therapeutic vulnerabilities and resistance mechanisms.

This postdoctoral position at Sapienza University in Rome focuses on developing bio-inspired regenerative medicine strategies using induced pluripotent stem cells, 3D bioprinting, biomaterials, and tissue engineering to model disease and create therapeutic solutions. The successful candidate will work on cardiac, skeletal muscle, and cancer systems, optimizing 3D in vitro models, designing biomimetic scaffolds, characterizing cell–matrix interactions, and collaborating with multidisciplinary teams of biologists, engineers, and clinicians to advance innovative regenerative therapies.

The Postdoctoral Associate position in the Weiss Lab at MIT focuses on microfluidics and biofabrication for advanced in vitro systems. The role involves designing and testing perfusion-enabled systems, developing biomaterials and biofabricated constructs, and contributing to interdisciplinary projects integrating engineering, biology, and biomaterials. Candidates will work on 3D bioprinting, organoid-based models, and organ-on-chip platforms, requiring expertise in microfluidic design, hydrogel formulation, and experimental system development.

This postdoctoral position in the Weiss Lab at MIT's Department of Biological Engineering focuses on advancing microfluidics and biofabrication technologies for creating perfusable, human-relevant in vitro systems. The successful candidate will design and test perfusion-enabled platforms, develop biomaterials and hydrogel-based scaffolds, and integrate 3D bioprinting techniques such as extrusion-based, SLA, and volumetric methods to produce organoid and organ-on-chip models. Collaboration with interdisciplinary teams will be essential to push the boundaries of microphysiological systems for disease modeling and drug testing.