neuronal cell conversion PostDoc positions and fellowships

The Postdoctoral Fellow in Computational Systems Biology at CIC bioGUNE will develop a computational platform to design neuronal cell conversion protocols for Alzheimer's disease, stroke, and epilepsy therapies. The role combines gene network-based approaches with machine learning models to predict transcription factor combinations for generating specialized neuronal subtypes. The candidate will collaborate with international experimental teams under a Canadian NFRF grant, contributing to stem cell research, aging, and disease modeling within a dynamic, interdisciplinary environment.

This 4-year PhD position at Delft University of Technology invites candidates to investigate the molecular assembly of neuronal synapses using cutting-edge cryo-electron tomography and complementary light microscopy. Working in Dr. Dimphna Meijer’s lab, the project aims to elucidate the nanoscale architecture of synaptic cell‑adhesion molecules and their functional implications in health and disease. The role combines hands‑on training in advanced structural biology techniques with opportunities for scientific independence within an international, supportive research environment.

Postdoctoral position developing computational platforms to identify cell fate conversion factors using gene network-based approaches and machine learning models. Focus on neurodegenerative diseases with collaboration at Ludwig Maximilian University of Munich.

This fully funded postdoctoral position at the University of Basel focuses on peripheral neuroscience and neuro-immune interactions within the Cancer Neuroimmunology lab led by Prof. Karen Dixon. The successful candidate will lead an interdisciplinary project investigating how peripheral neural signals regulate immune cell function in tissues and contribute to inflammatory or tumour-associated disease states. Research will employ neuronal tracing, in vivo disease models, genetic and viral manipulation of neuronal populations, imaging, flow cytometry, single‑cell RNA sequencing, spatial transcriptomics, and functional neuro‑immune assays.

This post-doctoral fellowship focuses on establishing and optimizing protocols for differentiating motor neurons from patient‑derived induced pluripotent stem cells (iPSCs) and applying cutting‑edge single‑cell proteomics to uncover disease‑relevant protein signatures in neuronal development. The researcher will integrate proteomic data with transcriptomics and imaging, collaborate with clinical partners on Parkinson’s and Alzheimer’s disease, and gain hands‑on experience with state‑of‑the‑art mass spectrometry instrumentation and computational analysis within an international, collaborative research environment at the Luxembourg Institute of Health.

The Postdoctoral Associate position in the Center for NeuroMetabolism at Rutgers Biomedical and Health Sciences focuses on investigating the molecular mechanisms regulating synaptic transmission in mammalian brain and human neurons derived from human tissue. The successful candidate will design and perform molecular biology, cell biology, and in vivo behavioral experiments, generate lentiviral vectors for gene delivery, and work with primary neuronal cultures, human fibroblasts, and pluripotent stem cells. Collaboration with the PI, Dr. Zhiping Pang, includes data analysis, manuscript preparation, grant writing, and training of undergraduate and graduate students.

A postdoctoral research fellow position is available at CIML, France, to investigate how sensory neurons regulate immune cell function during inflammation. The project uses mouse models and human cellular systems to uncover fundamental neuro-immune mechanisms and potential therapeutic avenues for inflammatory diseases.

This postdoctoral position at RIKEN focuses on the synthesis and study of organic semiconductor materials, with applications in devices like field-effect transistors, solar cells, and thermoelectric conversion. The role is part of the Emergent Molecular Function Research Group and offers a competitive salary, on-site work in Wako, Saitama, and a contract renewable for up to 5 years. Candidates should have a doctoral degree of less than 5 years and be prepared to contribute to a diverse and vibrant research environment.

This postdoctoral fellowship at the Luxembourg Institute of Health focuses on applying single-cell proteomics to study neuronal development using patient-derived induced pluripotent stem cells (iPSCs). The successful candidate will differentiate iPSCs into motor neurons, establish and optimize single-cell proteomics workflows, and integrate proteomic data with transcriptomics and imaging to uncover disease-relevant molecular signatures in Parkinson’s and Alzheimer’s disease. The position offers training in cutting-edge mass spectrometry, bioinformatics, and interdisciplinary collaboration within an international team.

The Heinrich lab at SBRI (INSERM U1208) is seeking a postdoc scientist to explore lineage reprogramming for brain repair. The project focuses on converting glial cells into functional induced neurons to replace lost neurons and induce functional recovery following brain injury or disease. The successful candidate will work at the interface of neurosciences, cell biology, and transcriptomics, investigating molecular programs underlying cell identity conversion and assessing therapeutic impact in mouse models of epilepsy.

This PhD position at the University of Barcelona focuses on developing innovative human-based in vitro and in silico brain models within the Horizon Europe MSCA VISI-ON-BRAIN doctoral network, investigating scaffold geometry and cell reprogramming effects on cortical progenitor proliferation, neuronal migration, and neurodevelopmental disorder models, and will enrol in the PhD programme while collaborating with international partners.

This postdoctoral fellowship focuses on deciphering the neurotoxic mechanisms of chitinase 3-like 1 (CHI3L1) in progressive multiple sclerosis and identifying therapeutic compounds that block its pathogenic effects. The successful candidate will work within the Clinical Neuroimmunology Group at VHIR, utilizing human iPSC-derived neuronal models, molecular and cellular biology, advanced imaging, transcriptomic and proteomic approaches, and drug screening strategies to uncover intracellular mediators, neuronal receptors, and potential drug candidates for progressive MS therapy.

The Postdoctoral Research Associate position in the Ly Lab at Washington University in St. Louis focuses on basic and translational research in motor neuron disease, including amyotrophic lateral sclerosis (ALS) and spinal muscular atrophy (SMA). The lab develops novel biofluid biomarkers and therapeutic targets using multimodal approaches such as cell culture, animal models, patient biosamples, mass spectrometry, and immunohistochemistry. The successful candidate will manage independent projects, aim for first-author publications, and gain expertise in immunoassays, Western blotting, qRT-PCR, proteomic data analysis, and ALS animal models, while contributing to grant preparation and scientific communication.