drug repurposing PostDoc positions and fellowships

The VHIR-MSCA-PF-2026.003 Postdoctoral Fellowship focuses on precision modelling of Familial Hypomagnesemia with Hypercalciuria and Nephrocalcinosis (FHHNC) using patient-derived kidney organoids to uncover disease mechanisms, phenotypic variability, and sex-specific aspects, while evaluating therapeutic candidates through drug repurposing. The successful candidate will join the Kidney Pathophysiology Research Group at Vall d'Hebron University Hospital in Barcelona, working within a multidisciplinary environment that integrates stem cell technology, genome engineering, and translational nephrology to advance understanding of this ultra-rare renal tubulopathy and develop novel precision medicine strategies.

A four‑year PhD position at Maastricht University Medical Centre+ focusing on health technology assessment and health economic modelling for precision medicine. The candidate will develop and apply modelling methods, collaborate with the REPO4EU consortium and NICE external assessment group, and contribute to health policy research within a multidisciplinary international team.

The successful candidate will develop and apply Computer-Aided Drug Design (CADD) methodologies to advance drug discovery projects, focusing on improving molecular understanding of ligand-protein interactions and translating these insights into the design of novel small-molecule, drug-like compounds. Working within a multidisciplinary team at Vrije Universiteit Amsterdam, the candidate will guide ongoing drug synthesis and biological screening activities, aiming to produce high-impact publications and contribute to new medicines for Alzheimer’s disease.

This PhD project at the University of Southampton develops silicon photonic sensors using mid-infrared light for instant therapeutic drug monitoring at point-of-care. Collaborating with NHS clinicians, the candidate will design and fabricate chips to detect drug concentrations, addressing critical gaps in treatment for medications with narrow therapeutic windows. Fully funded for 3.5 years, it offers access to Europe's top academic cleanrooms and state-of-the-art photonics labs within the UK's largest photonics center. Applicants require a 2:1 degree and will receive comprehensive technical and professional training in a supportive, inclusive research environment committed to sustainability and equality.

Postdoctoral Research Fellow position in Medicinal Chemistry and Drug Discovery at Northeastern University focusing on developing GPCR allosteric modulators and ligand-gated ion channel therapeutics for treating neuropathic pain, glaucoma, substance use disorder, and epilepsy. Requires Ph.D. in organic/medicinal chemistry with 1-3 years experience.

A postdoctoral research associate position is available at the University of Nebraska Medical Center’s Department of Biochemistry and Molecular Biology. The project focuses on developing and testing novel combination drug therapies for glioblastoma using advanced cell culture, 3D models, drug screening, fluorescence microscopy, and in vivo preclinical studies. The successful candidate will conduct animal genotyping, drug treatment, and breeding experiments, and is expected to have a PhD in Biochemistry, Biomedical Sciences, or Life Sciences, strong cancer biology expertise, and a track record of first‑author publications.

This postdoctoral position at the University of Sydney’s School of Chemistry focuses on medicinal chemistry and drug discovery, specifically lead candidate optimization projects selected by MedChem Australia. The successful candidate will conduct independent research, publish findings, assist with grant writing, and support teaching and supervision of undergraduate and postgraduate students. The role is full‑time, on‑site at the Camperdown campus, offering a competitive salary plus superannuation.

The Postdoctoral Research Associate in Medicinal Chemistry at the University of Sydney focuses on lead candidate optimization projects in partnership with MedChem Australia. The role involves designing, synthesizing, and evaluating novel bioactive compounds, publishing results, assisting grant writing, and supporting teaching and supervision of undergraduate and postgraduate students. Located on the Camperdown Campus, the position offers a competitive salary and a vibrant research environment.

A two-year Regulatory Affairs PharmD fellowship offered by Northeastern University in partnership with Ironwood Pharmaceuticals. The program provides training in global regulatory affairs, preparing fellows for industry roles through hands-on experience with regulatory submissions, strategies, and agency interactions.

The Postdoctoral Research Associate position in the Lu Lab at the University of Arizona focuses on developing innovative drug delivery systems, including prodrug conjugates and nanoformulations such as liposomes and polymeric nanoparticles, for cancer, cardiovascular, and neurodegenerative diseases. The role involves synthesizing and characterizing novel compounds, conducting in vitro and in vivo studies, preparing manuscripts, and presenting findings in group meetings and seminars. Candidates will benefit from a collaborative environment, access to cutting-edge facilities, and comprehensive university benefits.

This postdoctoral fellowship at NIDA focuses on neural engineering and behavioral neuroscience research, studying mechanisms of motivated behavior and drug relapse using advanced imaging techniques. The position offers competitive NIH stipend-based salary and is open to both US and international candidates.

The Wyss Institute at Harvard University seeks a Postdoctoral Fellow to lead innovative research at the intersection of artificial intelligence, synthetic biology, and drug discovery. The fellow will independently conduct research integrating AI methods with synthetic biology approaches to address challenges in drug discovery, present findings at internal meetings, mentor junior lab members, and contribute to grant writing and manuscript preparation. This one-year term position offers a competitive salary, benefits, and access to Harvard’s extensive resources, with potential extension based on performance and funding.