cardiac organoids PostDoc positions and fellowships

The University of Miami seeks a Post Doctoral Associate to conduct research in cardiovascular biology, heart failure, and regenerative medicine at their Interdisciplinary Stem Cell Institute. The role involves independent research, molecular assays, data analysis, manuscript preparation, and mentoring under supervision.

This PhD position at Eindhoven University of Technology focuses on uncovering universal mechanobiological gateways to cardiac regeneration by engineering cross‑species cardiac microtissue models. The candidate will quantify how mechanical and biochemical cues from the cellular microenvironment influence tissue response to injury, develop predictive hypotheses, and identify intervention strategies to steer repair toward regenerative outcomes. The project combines wet‑lab work, advanced imaging, and computational analysis within the Soft Tissue Engineering and Mechanobiology group.

The successful candidate will join the Bone Metabolism research group at the Instituto de Investigación Sanitaria del Principado de Asturias (ISPA) in Oviedo, Spain. The position involves hands-on work with laboratory animals, cell and tissue culture, and a wide range of histological and molecular biology techniques including DNA/RNA extraction, reverse transcription, genotyping, conventional and real-time PCR, Western blot, proteomics, and immunohistochemistry. Research will focus on evaluating vascular calcification, vascular and cardiac fibrosis, and senescence processes. This is a full-time, temporary postdoctoral role requiring a PhD or equivalent in Biological Sciences or a related field. The appointment is for one position, with applications due by June 28, 2026.

This PhD position focuses on cardiac immunometabolism, investigating interferon signaling's role in cardiocrine signaling and cardiac fibrosis using transgenic mouse models, hiPS-derived cardiomyocytes, and computational multi-omics analysis. The successful candidate will join Dr. Manju Kumari’s DFG-funded team at Heidelberg University’s Department of Cardiology, gaining expertise in molecular biology, animal work, and data integration while contributing to a collaborative interdisciplinary environment.

This PhD project at the University of Leicester aims to develop and apply machine learning techniques to diffusion MRI data for detecting subtle myocardial microstructural alterations in individuals with type 2 diabetes and early heart failure with preserved ejection fraction (HFpEF). The student will optimise acquisition and post‑processing pipelines to quantify biomarkers such as mean diffusivity, fractional anisotropy, helix angle and secondary eigenvector angle, contributing to early risk stratification and personalised management of cardiometabolic patients.

The Postdoctoral Fellow will work within the Department of Cardiovascular and Thoracic Surgery at Dell Medical School, University of Texas at Austin, collaborating with investigators in the Heart Center to generate and analyze clinical data aimed at improving patient outcomes in cardiac health. Responsibilities include conducting clinical research under mentor supervision, participating in study design, IRB submissions, informed consent, data collection and analysis, abstract and manuscript preparation, and presenting findings as part of a multidisciplinary team. The position offers initial one-year appointment renewable up to three years based on funding, performance, and progress, with a starting salary of $61,008+ adjusted according to NIH level.

This PhD position at ETH Zurich’s Singapore-ETH Centre focuses on developing advanced patient-derived bone organoids to model osteoporosis and fracture risk. The researcher will 3D print mesenchymal stromal cells, guide osteogenic differentiation under mechanical stimulation, and co-culture with peripheral blood mononuclear cells to study immune-bone interactions, donor-specific phenotypes, and mineralisation dynamics. Work involves molecular, biochemical, histological, imaging, and biomechanical techniques, complemented by computational analysis using Python and image processing. The project aims to create predictive models for personalised musculoskeletal care and fracture prevention strategies.

This PhD position focuses on probing the methylome in cardiac remodelling during pathology and aging to discover biomarkers of health and understand transcriptional changes. The candidate will develop and apply advanced bioinformatics and computational epigenomics tools for single-cell DNA methylome analysis of human heart tissue, leveraging access to over 500 cardiac samples from the KU/UZ Leuven biobank and collaborators in Antwerp. The project aims to generate high-resolution methylome maps of cardiomyocytes, fibroblasts, and other cardiac cell types, enabling epigenetic age prediction, bulk tissue deconvolution, and integrative analyses linking cardiac and blood DNA methylomes to uncover minimally invasive biomarkers for cardiac health and disease progression.

The ON‑Chip project seeks a postdoctoral researcher to design and fabricate micro‑ and millifluidic chips that recreate a human optic nerve‑on‑a‑chip platform. The work involves soft lithography, hot embossing, and clean‑room microfabrication to create fluidic channels linking retinal organoids to brain assembloids, incorporating microglial cells and genetically encoded biosensors for real‑time monitoring of retinal ganglion cell homeostasis under glaucomatous conditions such as neuroinflammation and elevated intra‑ocular pressure. The position is based at the Neuro‑SU department of CNRS in Paris, collaborating with Institut de la Vision and Institut du Cerveau, and is funded by the French PEPR MED‑OOC exploratory research program.

This postdoctoral position focuses on developing novel region-specific cortical organoid models from induced pluripotent stem (iPS) cells to study human cortex development and neurodevelopmental disorders. The successful candidate will differentiate iPS cells into cortical organoids that replicate cellular diversity and organization using microfluidic devices designed within the team, and will characterize the resulting cells via immunofluorescence and transcriptomic analyses. The role is situated within the Physique des Cellules et Cancer (UMR168) laboratory at Institut Curie in Paris, offering a highly interdisciplinary environment that combines physics, biology, biochemistry, and microbiology.