Biotechnology PostDoc positions and fellowships in Spain

Universidad Nebrija seeks a postdoctoral researcher in Bioinformatics, Big Data, and Translational Medicine to work on integrating omics, clinical, and medical imaging data for biomarker identification and computational healthcare approaches.

This postdoctoral fellowship at Vall d'Hebron University Hospital Research Institute focuses on elucidating how connexin 43 regulates intercellular communication in tumour-stroma interactions across breast, lung, and pancreatic cancers. The successful candidate will investigate tunnelling nanotube formation, mitochondrial transfer, extracellular vesicle signalling, and metabolic adaptation mechanisms driving cancer progression and therapy resistance, with access to advanced imaging, cell engineering platforms, and collaborative expertise in mitochondrial biology and EV research.

The position is for a postdoctoral researcher to work on the BIOCRAFT Horizon Europe project, developing climate-resilient, high-yielding rice lines using multiplex genome editing, AI-driven phenotyping, multi-omics, and microbiome–plant interaction studies. The researcher will focus on assessing tolerance of genome-edited rice to Magnaporthe oryzae (rice blast), conducting pathogen infection assays, phenotypic and molecular analyses, and integrating results into the breeding pipeline. The role involves collaboration with lab members and consortium partners, contribution to project reporting, manuscript preparation, and dissemination of outcomes.

The successful candidate will join the Bone Metabolism research group at the Instituto de Investigación Sanitaria del Principado de Asturias (ISPA) in Oviedo, Spain. The position involves hands-on work with laboratory animals, cell and tissue culture, and a wide range of histological and molecular biology techniques including DNA/RNA extraction, reverse transcription, genotyping, conventional and real-time PCR, Western blot, proteomics, and immunohistochemistry. Research will focus on evaluating vascular calcification, vascular and cardiac fibrosis, and senescence processes. This is a full-time, temporary postdoctoral role requiring a PhD or equivalent in Biological Sciences or a related field. The appointment is for one position, with applications due by June 28, 2026.

This postdoctoral fellowship, hosted by the Vall d'Hebron Research Institute in Barcelona, focuses on identifying and genetically engineering cytotoxic tissue‑resident natural killer (NK) cells for improved cellular immunotherapy against cancer and infectious diseases. The successful candidate will employ high‑dimensional phenotyping, single‑cell analyses, functional tissue models, and CRISPR‑based gene editing to characterize NK‑cell subsets with enhanced persistence and antitumor/antiviral activity, working within a collaborative international environment with access to cutting‑edge core facilities.

This postdoctoral fellowship focuses on deciphering the neurotoxic mechanisms of chitinase 3-like 1 (CHI3L1) in progressive multiple sclerosis and identifying therapeutic compounds that block its pathogenic effects. The successful candidate will work within the Clinical Neuroimmunology Group at VHIR, utilizing human iPSC-derived neuronal models, molecular and cellular biology, advanced imaging, transcriptomic and proteomic approaches, and drug screening strategies to uncover intracellular mediators, neuronal receptors, and potential drug candidates for progressive MS therapy.

The Vall d'Hebron Research Institute (VHIR) in Barcelona invites applications for a Marie Skłodowska-Curie Postdoctoral Fellowship focused on nucleotide homeostasis and mitochondrial function in neuromuscular and mitochondrial disorders. The successful candidate will investigate dNTP metabolism, mtDNA replication, and their link to OXPHOS function, aiming to develop therapeutic strategies for mitochondrial DNA maintenance disorders. The project combines cellular and mouse models with advanced biochemical, metabolomic, and genomic techniques, leveraging VHIR's core facilities. This fully funded fellowship offers international mobility, interdisciplinary training, and the opportunity to contribute to preclinical/clinical development of emerging therapies for severe mitochondrial diseases.