single-cell multiomics PhD positions, programs, scholarships and fellowships

This PhD position focuses on cardiac immunometabolism, investigating interferon signaling's role in cardiocrine signaling and cardiac fibrosis using transgenic mouse models, hiPS-derived cardiomyocytes, and computational multi-omics analysis. The successful candidate will join Dr. Manju Kumari’s DFG-funded team at Heidelberg University’s Department of Cardiology, gaining expertise in molecular biology, animal work, and data integration while contributing to a collaborative interdisciplinary environment.

The postdoctoral position at Utrecht University’s Department of Biology invites a highly motivated researcher to join the Bhardwaj lab and the Genome Biology and Epigenetics division as the founding member of the future quantitative genomics core unit (qGCu). The role focuses on leading independent projects in regulatory genomics of cell identity using cutting‑edge single‑cell and single‑molecule multi‑omics approaches, while also developing, adapting, and scaling these methods to make them accessible to the broader biology community. Successful candidates will collaborate with various research groups across Utrecht Science Park, contribute to core facility networking, and gain experience in a start‑up‑like environment that prepares them for academic leadership, industry roles, or entrepreneurial ventures.

The Senior Postdoctoral Research Assistant in Rheumatology at the University of Oxford will work within the Nuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Sciences (NDORMS) on a collaborative grant aimed at defining true disease‑free remission in inflammatory arthritis. The role involves leading experimental work that analyses tissue and blood samples, identifies reliable predictors of biological remission, and investigates pathways that promote freedom from disease using patient bio‑sample profiling, organoid formation, and multi‑omic techniques. The post‑holder will be supervised by Prof Chris Buckley and will collaborate closely with the Tissue Biology Lead Prof Mark Coles and the Computational/Bioinformatics Lead Dr Calliope Dendrou, contributing to a strategic alliance between Oxford and Birmingham. Responsibilities include developing analytical protocols, writing research articles for peer‑reviewed journals, presenting at national conferences, and leading seminars to disseminate findings. The position is a full‑time, fixed‑term appointment for 27 months with a salary range of £49,119–£58,265 per annum, and applications close on 13 July 2026.

The Machado Lab in the Departments of Pathology and Genetics at the University of Cambridge seeks a computational biologist/genomicist to analyse single‑cell genomic and transcriptomic data to study tumour‑immune co‑evolution during cancer progression.

This postdoctoral position at Adam Mickiewicz University in Poznań focuses on studying pancreatic organoids derived from type 2 diabetes patients using multi‑omics approaches. The researcher will differentiate human stem cells into pancreatic beta cells, apply CRISPR/Cas9 genome editing, and perform single‑cell RNA sequencing, proteomics, lipidomics, functional assays, and microscopic imaging. The project, funded by the National Science Center’s OPUS program, collaborates with groups in Helsinki and aims to advance cell and gene therapies for diabetes.

This postdoctoral position at the University of Oxford’s Nuffield Division of Clinical Laboratory Sciences focuses on developing a spatially resolved 3D atlas of bone marrow using advanced imaging, spatial transcriptomics, and computational pathology. The successful candidate will integrate AI-driven image analysis with molecular and clinical data to identify disease-associated features in blood cancer and skeletal injury, collaborating within the Wellcome-funded 3DxN consortium and gaining expertise in bioinformatics, machine learning, and multidisciplinary research.

Join the Quantitative Genomics Core Unit (qGCu) at Utrecht University’s Department of Biology, where you will work in the Bhardwaj lab under the guidance of Prof. Dr. Tuncay Baubec. The position focuses on developing and applying cutting‑edge single‑cell and single‑molecule technologies combined with innovative data science and bioinformatic methods to decipher regulatory control of cell fate decisions. You will collaborate with experts in genome biology, epigenetics, and developmental biology, and gain access to state‑of‑the‑art sequencing facilities at UMCU, Hubrecht and PMC.

A fixed-term (6‑month) Research Assistant/Research Associate position in the Khaled Lab at the University of Cambridge, focused on computational analysis of single‑cell and spatial transcriptomic data to understand and prevent hereditary breast cancer in BRCA1/2/PALB2 carriers.

This PhD position at the Netherlands Cancer Institute focuses on discovering tumor antigens and tumor‑reactive T‑cell receptors in renal cell carcinoma using the institute’s high‑throughput functional screening platform and single‑cell RNA sequencing. The candidate will work with patient samples from the NESCIO neoadjuvant clinical trial, generate TCR and antigen libraries, perform functional drop‑out screens, isolate tumor‑infiltrating lymphocytes, and evaluate their therapeutic potential. The project integrates translational immunology, bioinformatics, and clinical collaboration to advance personalized cancer vaccines and T‑cell‑based therapies.

This fully funded four-year PhD studentship at the Cancer Research UK Cambridge Institute invites applicants to investigate single-cell spatial multi-omics approaches in cancer biology, focusing on extrachromosomal DNA (ecDNA) and its role in oncogene amplification, tumour heterogeneity and therapy resistance. The successful candidate will develop and apply cutting‑edge imaging and epigenomic sequencing technologies to map gene regulation from single molecules to genome‑wide circuits, aiming to uncover new therapeutic targets in aggressive solid tumours. Training will be provided in interdisciplinary methods spanning molecular biology, genomics, microscopy and computation, within a world‑leading cancer research environment that offers access to state‑of‑the‑art core facilities and a vibrant postgraduate community.